Publicaciones

Patentes internacionales

Ganuza, E.T. (2024) Marine microalgal protein preparation. International application No. PCT/US2022/037344, filed July 15, 2022.

Ganuza, E.T., Amezquita, M and Sellers, C. (2018) Anaplerotic oils derived from algae. U.S. Patent 050O1HO17, filed January 2, 2018.

Shinde, S., Carney, L., Ganuza, E.T., Cizek, L., Hansen, J., Chellappan, G., Bennett, B., Sorensen, K., Ventre, S., Donowitz, N.A. and Rohlfsen, M.C (2017) Microalgae-based composition, and methods of its preparation and application to plants. International application No. WO/2017/218896 A1, published on December 21, 2017.

Ganuza, E., Amezquita, M., Sellers, C. and Sitek, A. (2017) Single stage fermentation methods of culturing oleaginous microorganisms. U.S. Patent 62/490,726, filed April 24, 2017.

Ganuza, E. and Sellers, C. (2016) Methods of applying ammonia toxicity and inducing nitrogen uptake in microalgae cultures. U.S. Patent 62/434,030, filed December 14, 2016.

Ganuza, E., Gonzalez, D. and Ganapathy, C. (2016) Phytohormone enriched microalgae methods and compositions. U.S. Patent 62/434,046, filed December 14, 2016.

Ganuza, E., Sellers, C., Sitek, A., Cobos, A., Hansen, J. and Lamont, M. (2016) Methods of culturing Aurantiochytrium using acetate as an organic carbon source. U.S. Patent 62/402,757, filed September 30, 2016.

Ganuza, E., Sellers, C., Paolilli, K., Amezquita, M. and Hansen, J. (2016) Methods for applying acetate toxicity and inducing acetate uptake in microalgae cultures. U.S. Patent 62/402,794, filed September 30, 2016.

Ganuza, E., and Olaizola, M. (2016) Methods of treating wastewater with microalgae cultures supplemented with organic carbon. U.S. Patent 030M2HO16091601, filed September 16, 2016.

Ganuza, E., Paolilli, K., Barrett, R., Cizek, L. Cobos, A. and Oelschlager, M., (2016) Systems and methods for continuous mixotrophic culturing of microalgae. U.S. Patent 62/351,415, filed June 17, 2016.

Ganuza, E., Paolilli, K. and Lyons, E., (2016) Methods for controlling malic acid excretion in microalgae cultures. U.S. Patent 62/302,233, filed March 2, 2016.

Ganuza, E. and Tonkovich, A.L. (2015) Method of treating bacterial contamination in microalgae with pH shock. U.S. Patent WO2014/074,769 A2, filed December 29, 2014 and issued November 10, 2015.

Ganuza, E., Licamele, J.D., Tonkovich, A.L, Bellefeuille, M.V., Wyatt, C., Kulaga, T.J. and Galvez, A. (2015) Balanced mixotrophy methods. U.S. Patent WO2014/074,770 A2 filed April 29, 2014 and issued August 27, 2015.

Ganuza, E., Licamele, J.D., Tonkovich, A.L, Bellefeuille, M.V., Wyatt, C., Kulaga, T.J. and Galvez, A. (2015) Mixotrophic, phototrophic, and heterotrophic combination methods and systems. U.S. Patent WO2014/074,772 A1, filed April 29, 2015 and issued August 20, 2015.

Ganuza, E., Tonkovich, A.L. and Licamele, J.D. (2015) Methods of culturing microorganisms in non-axenic mixotrophic conditions. U.S. Patent WO2014/074,769 A3 filed

December 30, 2014 and issued April 30, 2015.Tonkovich, A.L., Licamele, J.D., Ganuza, E., Galvez, A., Sullivan, T.J., Adame, T. and Esler, J. (2014) Large scale mixotrophic production systems. U.S. Patent WO2014/144,270 A1 filed March 14, 2014 and issued September 18, 2014.

Tonkovich, A.L., Adame, T., Qin, S. and Ganuza, E. (2015) Bioreactor array and methods of combinatorial testing. U.S. Patent WO2014/130,357 A1 filed February 14, 2014 and issued August 25, 2014.

Ganuza, E. (2015) Microalgae as a mineral vehicle in aquafeeds. U.S. Patent 2013/0205850 A1 filed February 13, 2013 and issued August 15, 2013.

Ganuza, E., Licamele, J.D., Tonkovich, A.L. and Shinde, S. (2013) Methods of growing vascular plants with mixotrophic microalgae. International application No. PCT/US2013/069037 filed November 8, 2013.

Ganuza, E., Licamele, J.D., Tonkovich, A.L. and Shinde, S. (2013) Methods of making cosmetic compositions with mixotrophic microalgae. International application No. PCT/US2013/069040 filed November 8, 2013.

Ganuza, E., Licamele, J.D., Tonkovich, A.L. and Shinde, S. (2013) Methods of making food and feed compositions with mixotrophic microalgae. International application No. PCT/US2013/069042 filed November 8, 2013.

Ganuza, E., Licamele, J.D., Tonkovich, A.L. and Shinde, S. (2013) Methods of making fuel, bioplastic, and chemical compositions with mixotrophic microalgae. International application No. PCT/US2013/069043 filed November 8, 2013.

Ganuza, E., Licamele, J.D., Tonkovich, A.L. and Shinde, S. (2013) Methods of supplying nutrients in closed environments with mixotrophic microalgae. International application No. PCT/US2013/069044 filed November 8, 2013.

Ganuza, E., Licamele, J.D., Tonkovich, A.L. and Shinde, S. (2013) Methods of treating wastewater with mixotrophic microalgae. International application No. PCT/US2013/069050 filed November 8, 2013.

Ganuza, E., Licamele, J.D., Wyatt, C.M., Galvez, A. and Shinde, S. (2013) Mixotrophy technology. U.S. Provisional application No. 61/799151 filed March 15, 2013.

Ganuza, E., Licamele, J.D., Wyatt, C.M., Kulaga, T.J., Galvez, A., Tonkovich, A.L, Bellefeuille, M.V., Ventre, S.J., Kale, A., Shinde, S. and Flores, A.C. (2013) Mixotrophy systems and methods. U.S. Provisional application No. 61/798969 filed March 15, 2013.

Ganuza, E. (2013) Production of Omega-7 fatty acid. U.S. Provisional application No. 61/884408 filed September 30, 2013.

Ganuza, E. and Izquierdo M. (2008) Procedimiento para la producción de biomasa rica en ácidos grasos poliinsaturados, entre ellos DHA, a partir del cultivo de un Traustochytrido en condiciones no limitantes de nitrógeno, mediante el empleo de un sistema de control del pH que regula el suministro de la fuente de nitrógeno. Spanish patent 2,333,571 A1 filed March 7, 2008.

Artículos científicos

Enríquez, J., Quezada, C., Molina, J., Sáez, M., Mitre, I., Moreira, C., Sandoval, F., Maldonado, R., Fito, M., Zagmutt, M., Ramírez-Contreras, C., Ganuza, E., Hernández, A., Martínez-Huenchullán, S. & Sandoval V. (2025) Study protocol and baseline cardiometabolic characterization of the RIO-Study (Response to an intervention with Omega-3): A randomized, double-blind, placebo-controlled crossover trial on lipid and inflammatory profiles in overweight and obese adults with hypertriglyceridemia in Valdivia, Chile. Nutrition, 11:3943756.

Ganuza, E., Etomi, E.H., Olson, M. & Whisner C.M. (2024) Omega-3 eicosapentaenoic polar-lipid rich extract from microalgae Nannochloropsis decreases plasma triglycerides and cholesterol in a real-world normolipidemic supplement consumer population. Frontiers in Nutrition, 11:1293909.

Global Organization for EPA and DHA Omega-3s (GOED) Technical Team (2023) Technical report: Conversion factors for polar lipids and expression of EPA, DHA and total omega-3 content in polar lipid oils. GOED Technical Guidance Documents, September 10th.

Sanchez, M.R., Biondi, T.C., Kunde, Y.A., Eng, W., Nalley, J.O., Ganuza, E., Hovde, B.T., Corcoran, A.A. & Starkenburg, S.R (2022) The Genome Sequence of an Algal Strain of Nannochloropsis QH25. Microbiology Resource Announcements, 11(12), 921–922.

Rao, A., Briskey, D., Nalley, J.O., Ganuza, E. (2020). Omega-3 eicosapentaenoic acid (EPA) rich extract from the microalga Nannochloropsis decreases cholesterol in healthy individuals: a double-blind, randomized, placebo-controlled, three-month supplementation study. Nutrients, 12, 1-14.

Ganuza, E., Amezquita, M., Giraldo-Silva, A., Wang, S. and Andersen, A.A., (2020) Genomics, biology and phylogeny Aurantiochytrium acetophilum sp. nov. (Thraustrochytriaceae), including first evidence of sexual reproduction. Protist, 170, 209–232.

Andersen, A.A. and Ganuza, E. (2018) Nomenclatural errors in the Thraustochytridales (Heterokonta–Staminipila), especially with regard to the type species of Schizochytrium. Notulae algarum, 64, 1–8.

Ganuza, E., Paolilli, K., Sellers, C.E., Amezquita, M. (2018) Strategies for mass production of mixotrophic microalgae. 12th Algae Biomass Summit. Conference proceedings, Houston, Texas (USA).

Sellers, C. and Ganuza E. (2017) The narrow balance of feeding charged nutrients. 12th Recent Advances in Fermentation Technology (RAFT12). Conference proceedings, Bonita Springs (Florida).

Ganuza, E., Sellers, C. E. and Amezquita, M. (2017) Engineering acetic acid toxicity to grow mixotrophic microalgae at scale. 11th International Phycological Congress IPC11. Conference proceedings, Szczecin (Poland).

Ganuza, E., Sellers, C. E., Bennett, B. W., Lyons, E. M., and Carney L.T. (2016) A novel treatment protects Chlorella at commercial scale from the predatory bacterium Vampirovibrio chlorellavorus. Frontiers in Microbiology, 7, 848.

Ganuza E. and Tonkovich, L. (2016) Heliae, an industrial approach to mixotrophy in microalgae. Book Chapter in: Industrial Biorenewables: A practical viewpoint. 616. Pablo Dominguez de Maria (Ed) John Wiley and Sons. Hoboken, US.

Ganuza, E., Sellers, C. E., Bennett, B. W., Lyons, E. M., and Carney L.T. (2016) A novel treatment protects Chlorella at commercial scale from the predatory bacterium Vampirovibrio chlorellavorus. Frontiers in Microbiology, 7, 848.

Ganuza, E., Sellers, C. E., Bennett, B. W., Lyons, E. M., and Carney L.T. (2016) A novel treatment protects Chlorella at commercial scale from the predatory bacterium Vampirovibrio chlorellavorus. 10th Algae Biomass Summit. Conference proceedings, Glendale, Arizona (USA).

Eryalcin K.M., Ganuza E., Atalah E. and Hernandez-Cruz C.M. (2015) Nannochloropsis gaditana and Crypthecodinium cohnii, two microalgae as alternative sources of essential fatty acids in early weaning for gilthead seabream (Sparus aurata). Hidrobiologica, 25(2), 193-203.

Ganuza E.(2015) Mixotrophic fermentation: Methods to scale up the full potential of microalgae. Recent Advances in Fermentation Technology RAFT11. Conference proceedings, Clearwater Beach, FL (USA).

Carney, L. and Ganuza E. (2015) Crop Protection: An essential component of cultivation. Algae Biomass Summit. Conference proceedings, Washington, DC (USA).

Carney, L. and Ganuza E. (2015) A multi–platform, multi-strain pathway to commercialization. Food and Fuel for the 21st Century Symposium, Green Revolution 2.0. Conference proceedings, San Diego, CA (USA).

Ganuza E. and Tonkovich, L. (2014) Pioneering industrial culture of mixotrophic microalgae. Recent Advances in Microbial Control, RAMC2014. Conference proceedings.

Ganuza E., Moya C., Said M. and Caballero V. (2011) Large scale microalgae production and processing for the hatchery market. 12th International Conference on Applied Phycology. Journal of Applied Phycolgical Society, 52, 70 (ed.), Halifax (Canada).

Atalah E., Hernández-Cruz C.M., Ganuza E., Benítez-Santana T., Ganga R., Roo J., Montero D. and Izquierdo, M.S. (2011) Importance of dietary arachidonic acid for the growth, survival and stress resistance off larval European sea bass (Dicentrarchus labrax) fed high dietary docosahexaenoic and eicosapentaenoic acid. Aquaculture Reseach, 42(9), 1261–1268.

Ganga R., Montero D., Bell J.G., Atalah E., Ganuza E., Vega-Orellana O., Tort L., Acerete L., Afonso J.M., Benítez-Santana T., Fernández-Vaquero A. and Izquierdo M.S. (2011) Stress response in sea bream (Sparus aurata) held under crowded conditions and fed diets containing linseed and/or soybean oil. Aquaculture, 311, 215-223.

Ganuza E., Benítez-Santana T., Atalah E., Vega-Orellana O., Ganga R. and Izquierdo, M.S. (2008) A trophic step in aquaculture: algae as fish oil substitutes. 11th International Conference on Applied Phycology, Journal of Applied Phycology Society, 32, 121–122 (ed.), Galway (Ireland).

Ganuza E., Anderson A.J. and Ratledge C. (2008) High-cell-density cultivation of Schizochytrium in ammonium-pH-auxostat fed-batch system. Biotechnol Lett, 30(9), 1559–1564.

Ganuza E., Benítez-Santana T., Atalah E., Vega-Orellana O., Ganga R. and Izquierdo M.S. (2008) Crypthecodinium cohnii and Schizochytrium sp. as potential substitutes to fisheries derived oils in Sparus aurata microdiets. Aquaculture, 277, 100–116.

Ganuza E. and Izquierdo M.S. (2007) Lipid accumulation in Schizochytrium G13/2S produced in continuous culture. Applied Microbilogy and Biotechnology, 270 (76), 985–990.

Benítez-Santana T., Masuda R., Juárez-Carrillo E., Ganuza E., Valencia A., Hernández-Cruz C.M. and Izquierdo M.S. (2007) Dietary n-3 HUFA deficiency induces a reduced visual response in gilthead seabream Sparus aurata larvae. Aquaculture, 264 (1–4), 408–417.

Izquierdo M.S., Benítez–Santana T., Atallah E., Ganuza E., Roo J. and Hernández-Cruz, C.M. (2006) Lipid nutrition and lipid sources for marine fish larvae. In Aqua 2006: The Annual Meeting of the World Aquaculture Society Florence (Italy).

Ganuza E., Ratledge C. and Izquierdo M.S. (2005) High-cell-density cultivation of Schizochytrium sp. in ammonia-pH-auxostat fed-batch system. In 8th International Phycological Congress. Journal of the International Phycology Society, 44, 120 Kawai, H. (ed.) Durban (South Africa).

Ganuza E., Ratledge C., Anderson A.J., and Izquierdo, M.S. (2005) Lipid accumulation in Schizochytrium G13/2S under continuous culture. In 12th European Congress of Biotechnology, ”Bringing genomes to life” Journal of Biotechnology, 118, 189 Puhler, A. (ed.) Copenhagen (Denmark).

Benítez-Santana T., Masuda R., Valencia A., Hernández-Cruz C.M., Juárez-Carrillo E.., Ganuza E. and Izquierdo M.S. (2004) Effect of dietary lipids on larval gilthead seabream (Sparus aurata, L.) behavior.